Education & Career

01/2014 - ...		Professor University of Bordeaux affiliated to the CRPP-CNRS	Bordeaux, France
2016		Junior Member of the Institut Universitaire de France University of Bordeaux	Pessac, France
2010 - 12/2013		Independent Max Planck Research Group Leader Droplets, Membranes and Interfaces - MPI for Dynamics and Self-Organisation	Goettingen, Germany
2009 - 2010		Group Leader Department Herminghaus, Physics of Complex fluids - MPI for Dynamics and Self-organisation	Goettingen, Germany
2005 - 2009		Post-doc Laboratoire de Biologie Chimique - ISIS-UdS-CNRS	Strasbourg, France
2002 - 2005		PhD Thesis Philips Research Labs and University of Twente	Eindhoven and Enschede, The Netherlands
2001 - 2002		Master of Fluid Physics Universite Pierre et Marie Curie	Paris, France
1996 - 2002		Physics and Chemistry Studies ESPCI	Paris, France

PhD Thesis

Morphological transitions in simple electrocapillary systems: Tools for microfluidic liquid manipulation J.-C. Baret Twente University, 2005

Group Publications

Rectifying jet breakup by electric forcing D. van Assche, T. Beneyton, and J.-C. Baret Droplet (2023)

Droplet-based microfluidics T. Moragues, D. Arguijo, T. Beneyton, C. Modavi, K. Simutis, A.R. Abate, J.-C. Baret, A.J. de Mello, D. Densmore, and A.D. Griffiths Nature Reviews Methods Primers (2023)

Coacervate droplets for synthetic cells Z. Lin, T. Beneyton, J.-C. Baret, and N. Martin Small Methods, 2023

Oil conductivity controls electrocoalescence in inverse emulsions D. van Assche, T. Beneyton and J.-C. Baret Submitted, 2023

Frontiers in single cell analysis: multimodaltechnologies and their clinical perspectives J. Kallberg, W. Xiao, D. van Assche, J.-C. Baret, and V. Taly Lab Chip (2022)

A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation M. Scheffen, D.G. Marchal, T. Beneyton, S. K. Schuller, M. Klose, C. Diehl, J. Lehmann, P. Pfister, M. Carrillo, H. He, S. Aslan, N. S. Cortina, P. Claus, D. Bollschweiler, J.-C. Baret, J. M. Schuller, J. Zarzycki, A. Bar-Even and T. J. Erb Nature Catalysis (2021)

Fast and Ample Light Controlled Actuation of Monodisperse All-DNA Microgels R. Merindol, N. Martin, T. Beneyton, J.-C. Baret, S. Ravaine Advanced Functional Materials, 2010396 (2021)

Variable inter- and intra-species alkaline phosphatase activity within single cells of revived dinoflagellates M. Girault, R. Siano, C. Labry, M. Latimier, C. Jauzein, T. Beneyton, L. Buisson, Y. Del Amo, J.-C. Baret The ISME Journal (2021)

From collections of independent, mindless robots to flexible, mobile, anddirectional superstructures J. F. Boudet, J. Lintuvuori, C. Lacouture, T. Barois, A. Deblais, K. Xie, S. Cassagnere, B. Tregon, D. B. Brueckner, J.-C. Baret, H. Kellay Science Robotics (2021)

Confining Trypanosoma brucei in emulsion droplets reveals population variabilities in division rates and improves in vitro cultivation S. Oldenburg, L. Buisson, T. Beneyton, D. Pekin, M. Thonnus, F. Bringaud, L. Riviere and J.-C. Baret Scientific Reports, 11, 18192 (2021)

Directed evolution in drops: molecular aspects and applications A. Manteca, A. Gadea, D. van Assche, P. Cossard, M. Gillard-Bocquet, T. Beneyton, A. Innis, J.-C. Baret ACS Synthetic Biology (2021)

High-Throughput Synthesis and Screening of Functional Coacervates Using Microfluidics T. Beneyton, C. Love, M. Girault, T.Y. D. Tang, J.-C. Baret Chem. Systems Chem. 2, e2000022 (2020)

Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts T. E. Miller, T. Beneyton, T. Schwander, C. Diehl, M. Girault, R. McLean, T. Chotel, P. Claus, N. Socorro Cortina, J.-C. Baret, T.J. Erb Science 368, 6491, pp. 649-654 (2020)

Formulations for microfluidics F. Maes and J.-C. Baret Actualite Chimique, 453, 59-60 (2020)

Microfluidic technology for plankton research M. Girault, T. Beneyton, Y. Del Amo and J.-C. Baret Current Opinion in Biotechnology, 55, 134-150 (2019)

Rational design of a high-throughput droplet sorter S S. Schuetz, T. Beneyton, J.-C. Baret, T.M. Schneider Lab chip, 19, 2220 (2019)

Rapid Stabilization of Droplets by Particles in Microfluidics: Role of Droplet Formation L.A. Chacon, J.-C. Baret Chem Systems Chem, 1, 16-24 (2019)

High-Throughput Triggered Merging of Surfactant-Stabilized Droplet Pairs Using Traveling Surface Acoustic Waves V. Bussiere, A. Vigne, A. Link, J. McGrath, A. Srivastav, J.-C. Baret, T. Franke Anal. Chem. 91, 21, 13978-13985 (2019)

From Compartmentalization of Bacteria within Inorganic Macrocellular Beads to the Assembly of Microbial Consortia A. Roucher, M. Morvan, D. Pekin, M. Depardieu, J.-L. Blin, V. Schmitt, M. Konrad, J.-C. Baret and R. Backov Advanced Biosystems, 2, 1700233 (2018)

High-Content Screening of Plankton Alkaline Phosphatase Activity in Microfluidics M. Girault, T. Beneyton, D. Pekin, L. Buisson, S. Bichon, C. Charbonnier, Y. del Amo, and J.-C. Baret Analytical Chemistry 90 (6), 4174-4181 (2018)

Boundaries control collective dynamics of inertial self-propelled robots A. Deblais, T. Barois, T. Guerin, P. H. Delville, R. Vaudaine, J. S. Lintuvuori, J. F. Boudet, J.-C. Baret, and H. Kellay Physical Review Letters, 120, 188002(2018)

Preparation of swellable hydrogel-containing colloidosomes from aqueous two-phase Pickering emulsion droplets J-P Douliez, N. Martin, T. Beneyton, J.-C. Eloi, J-P Chapel, L. Navailles, J.-C. Baret, S. Mann, L. Beven Angewandte Chemie International Edition, 57, 7780-7784 (2018)

MaxSynBio - Avenues towards creating cells from the bottom up P. Schwille, J. Spatz, K. Landfester, E. Bodenschatz, S. Herminghaus, V. Sourjik, T. Erb, P. Bastiaens, R. Lipowsky, A. Hyman, P. Dabrock, J.-C. Baret, T. Vidakovic-Koch, P. Bieling, R. Dimova, H.Mutschler, T. Robinson, D. Tang, S. Wegner, and K. Sundmacher Angewandte Chemie International Edition, 57, 13382-13392 (2018)

Out-of-equilibrium microcompartments for the bottom-up integration of metabolic functions T. Beneyton, D. Krafft, C. Bednarz, C. Kleineberg, C. Woelfer, I. Ivanov, T. Vidakovic-Koch, K. Sundmacher and J.-C. Baret Nature Communications, 9:2391 (2018)

High throughput multiplexed fluorescence activated droplet sorting O. Caen, S. S. Schuetz, M.Jammalamadaka, J. Vrignon, P. Nizard, T. Schneider, J.-C. Baret and V. Taly Microsystems and Nanoengineering, 4 (2018)

Microfluidic angle of repose test for Pickering emulsions L.A. Chacon and J.-C. Baret Journal of Physics D: Applied Physics, 50, 39 (2017)

High throughput single cell counting in droplet-based microfluidics H. Lu, O. Caen, J. Vrignon, E. Zonta, Z. El Harrak, P. Nizard, J.-C. Baret & V. Taly Scientific Reports 7, 1366 (2017)

Catanionic Coacervate Droplets as a Surfactant-Based Membrane-Free Protocell Model J.-P. Douliez, N. Martin, C. Gaillard, T. Beneyton, J.-C. Baret, S. Mann, L. Beven Angewandte Chemie International Edition, 56, 44, 13689 (2017)

AC electrified jets in a flow-focusing device: Jet length scaling E. Castro-Hernandez, P. Garcia-Sanchez, J. Alzaga-Gimeno, S.H.Tan, J.-C. Baret and A. Ramos Biomicrofluidics 10, 043504 (2016)

Vesicles-on-a-chip: A universal microfluidic platform for the assembly of liposomes and polymersomes. J. Petit, I. Polenz, J.-C. Baret, S. Herminghaus, O. Baeumchen Eur Phys J E Soft Matter, 39: 59 (2016)

Controlling molecular transport in minimal emulsions P. Gruner, B. Riechers, B. Semin, J. Lim, A. Johnston, K. Short, J.-C. Baret Nature Communications, 10392 (2016)

Surfactant adsorption kinetics in microfluidics B. Riechers, F. Maes, E. Akoury, B. Semin, P. Gruner, and J.-C. Baret Proceedings of the National Academy of Sciences U.S.A, 113, 41, 11465-11470 (2016)

Digital PCR compartmentalization. I. Single molecule detection of rare mutations K. Perez-Toralla, D. Pekin, J.-F. Bartolo, F. Garlan, P. Nizard, P. Laurent-Puig, J.-C. Baret and V. Taly Medecine Sciences 31 : 84-92 (2015)

Monitoring Reactive Microencapsulation Dynamics using Microfluidics I. Polenz, Q. Brosseau and J.-C. Baret Soft Matter, 11, 2916-2923 (2015)

Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays J. Lim, O. Caen, J. Vrignon, M. Konrad, V. Taly and J.-C. Baret Biomicrofluidics 9, 034101 (2015),

Breakup length of AC electrified jets in a microfluidic flow-focusing junction E. Castro-Hernández, P. García-Sánchez, S. H. Tan, A. M. Gañán-Calvo, J.-C. Baret, and A. Ramos Microfluidics Nanofluidics, 19, 4, 787 (2015)

Stabilisers for water-in-fluorinated-oil dispersions: key properties for microfluidic applications P. Gruner, B. Riechers, L. A. Chacòn Orellana, Q. Brosseau, F. Maes, T. Beneyton, D. Pekin, J.-C. Baret Current opinion in colloid and interface science, 20, 3, 183-191 (2015)

Microfluidic Flow-Focusing in ac Electric Fields S. H. Tan, B. Semin and J.-C. Baret Lab Chip, 14, 1099-1106 (2014)

Enhanced chemical synthesis at soft interfaces: A universal reaction-adsorption mechanism in microcompartments A. Fallah-Araghi, K. Meguellati, J.-C. Baret, A. El Harrak, T. Mangeat, M. Karplus, S. Ladame, C. M. Marques, and A. D. Griffiths Physical Review Letters, 112, 028301 (2014)

Microfluidic Dynamic Interfacial Tensiometry (μDIT) Q. Brosseau, J. Vrignon and J.-C. Baret Soft Matter, 10, 3066-3076 (2014)

The Microfluidic Puzzle: Chip-oriented Rapid Prototyping. J. Lim, F. Maes, V. Taly and J.-C. Baret Lab Chip, 14, 1669-1672 (2014)

CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in E. coli using droplet-based microfluidics T. Beneyton, F. Coldren, J.-C. Baret, A. Griffiths and V. Taly Analyst, 139(13):3314-23 (2014 )

The Microfluidic Jukebox S. H. Tan, F. Maes, B. Semin, J. Vrignon and J.-C. Baret Scientific Reports 4, 4787 (2014)

Wetting heterogeneities in porous media control flow dissipation J. Murison, B. Semin, J.-C. Baret, S. Herminghaus, M. Schroeter and M. Brinkmann Physical Review Applied 2, 034002 (2014)

Micro-optical lens array for fluorescence detection in droplet-based microfluidics J. Lim , P. Gruner , M. Konrad, J.-C. Baret Lab Chip, 13, 1472-1475 (2013)

Enhanced imine synthesis in water: from surfactant-mediated catalysis to host-guest mechanisms K. Meguellati, A. Fallah-Araghi, J.-C. Baret, A. El Harrak, T. Mangeat, C. Marques, A. Griffiths and S. Ladame Chem. Commun., 49,11332-11334 (2013)

Ultra-high throughout detection of single cell β-galactosidase activity in droplets using micro-optical lens array J. Lim, J. Vrignon, P. Gruner, C. Karamitros, M. Konrad, and J.-C. Baret Applied Physics Letters, 103,20 (2013)

Surfactants in droplet-based microfluidics J.-C. Baret Lab Chip 12, 422-433 (2012)

Dynamics of molecular transport by surfactants in emulsions Y. Skhiri, P. Gruner, B. Semin, Q. Brosseau, D. Pekin, L. Mazutis, V. Goust, F. Kleinschmidt, A. El Harrak, J.B. Hutchison, E. Mayot, J.-F. Bartolo, A.D. Griffiths, V. Taly, J.-C. Baret Soft Matter 8, 10618-10627 (2012)

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution J. J. Agresti, E. Antipov, A. R. Abate, K. Ahn, A. C. Rowat, J.-C. Baret, M. Marquez, A. M. Klibanov, A. D. Griffiths, and D. A. Weitz Proc. Natl. Acad. Sci. U S A 107 (2010) 4004

High-throughput screening of enzymes by retroviral display using droplet-based microfluidics L. Granieri, J.-C. Baret, A. D. Griffiths, and Ch. A. Merten Chem Biol 17 (2010) 229

Quantitative cell-based reporter gene assays using droplet-based microfluidics J.-C. Baret, Y. Beck, I. Billas-Massobrio, D. Moras and A.D. Griffiths Chem Biol 17 (2010) 528

Chapter 17 - Tiny Droplets for High-Throughput Cell-Based Assays J.-C. Baret and V. Taly in: Unravelling Single Cell Genomics: Micro and Nanotools Nathalie Bontoux (Editor), Luce Dauphinot (Editor), Marie-Claude Potier (Editor), ISBN: 978-1-84755-911-1

Kinetic aspects of emulsion stabilization by surfactants: a microfluidic analysis J.-C. Baret, F. Kleinschmidt, A. El Harrak, and A. D. Griffiths Langmuir 25, 6088 (2009)

Droplets and emulsions: very high-throughput screening in biology J.-C. Baret, V. Taly, M. Ryckelynck, Ch. A. Merten, and A. D. Griffiths Med. Sci. 25, 627 (2009)

Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms J. Clausell-Tormos, D. Lieber, J.-C. Baret, A. El-Harrak, O. J. Miller, L. Frenz, J. Blouwolff, K. J. Humphry, S. Koester, H. Duan, C. Holtze, D, A. Weitz, A. D. Griffiths, and C. A. Merten Chem Biol 15, 427 (2008)

Self-excited drop oscillations in electrowetting J.-C. Baret, M. M. J. Decre and F. Mugele Langmuir 23, 5173 (2007)

Electrical discharge in capillary breakup: controlling the charge of a droplet J.-C. Baret, and F. Mugele Phys. Rev. Lett. 96, 016106 (2006)

Wettability control of droplet deposition and detachment J.-C. Baret and M. Brinkmann Phys. Rev. Lett. 96, 146106 (2006)

Microfluidic mixing through electrowetting-induced droplet oscillations F. Mugele, J.-C. Baret, and D. Steinhauser Appl. Phys. Lett 88, 204106 (2006)

Electrowetting: from basics to applications F. Mugele, and J.-C. Baret J. Phys. Condens. Matter 17 (2005) R705

Gravity driven flow of viscous liquid over two-dimensional topographies M. Decre and J.-C. Baret J. Fluid Mechanics 487 147-166 (2003)

Extremal Model for Amorphous Media Plasticity J.-C. Baret, D. Vandembroucq, and S. Roux Phys. Rev. Lett. 89 195506 (2002)

Proceedings

Microfluidic Approaches for the Study of Emulsions: Transport of Solutes P. Gruner, Y. Skhiri, B. Semin, Q. Brosseau, A. D. Griffiths, V. Taly and J.-C. Baret Material Research Society (MRS), Volume 1530 (2013)